Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.

Ann Clin Transl Neurol · 2015 · PMC4693592 · PMID 26734659

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highly significantno p-value reported

2 A), with highly significant differences seen between MS patients and HV, irrespective of myelin phagocytosis.

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did not reach statistical significanceno p-value reported

Interestingly, phagocytosis of myelin debris itself demonstrated a tendency for monocytes to downmodulate surface CD14 and upregulate sCD14 in the supernatants, even though these changes did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.