highly significantp-values < 0.001
P-values < 0.05 were considered statistically significant (*), p-values < 0.01 were considered highly significant (**) and p-values < 0.001 were considered very highly significant (***).
P-values < 0.05 were considered statistically significant (*), p-values < 0.01 were considered highly significant (**) and p-values < 0.001 were considered very highly significant (***).
Interestingly, the inverse is also true: we show that the inhibition of PAI-1 function leads to decreased VE-cadherin levels in endothelial cells, albeit the differences we observed did not reach statistical significance.