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RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway.

Oncotarget · 2015 · PMC4694831 · PMID 26325371

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Besides, compared with vehicle, CDDP treatment reduced body weight of mice, while the RY-2f and combined treatment slightly reduced body weight, but did not reach statistical significance (Figure 6F ).

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