Endothelial Gata5 transcription factor regulates blood pressure.

Furthermore, we also found a strong trend to increased protein nitrotyrosination (a hallmark of oxidative stress) in Gata5 -null mice mesenteric arteries ( P =0.076, t -test) ( Fig. 3j ), reflecting a possible imbalance in oxidative stress that may contribute to decreased NO bioavailability 22 .

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