Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands.

Additional support for the model was also provided when considering results with the H242A 6.55 mutant as, although the results did not reach statistical significance, this mutation tended to reduce affinity for CATPB but not GLPG0974 ( Table 2 ).

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