Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma.

PLoS One · 2015 · PMC4699826 · PMID 26714314

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did not reach statistical significanceno p-value reported

In the case of CD163+ TAMs, their low density showed a tendency to have more frequent vascular invasion ( p = 0.124) and low BMI status ( p = 0.077) but did not reach statistical significance.

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marginally significantno p-value reported

To sum up the above data, high density of CD163+ TAMs was significantly associated with prolonged DFS in MSI-H GCs, but in the cases of CD68+ TAMs, high density was marginally significant in predicting patients’ good clinical outcome.

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