MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199.

Cell Rep · 2015 · PMC4700051 · PMID 26711339

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did not reach statistical significanceno p-value reported

Patients with t(4;11) (n = 12) expressed high levels of BCL-2, BAX, and BIM ( Figure 1 ) but relatively low levels of BCL-X L and MCL-1, although the latter differences did not reach statistical significance.

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