Although these changes did not reach statistical significance, because of interdonor variability in these primary hPDLSC cultures, these results suggest that LXA 4 may stimulate the production of SPMs by hPDLSCs, likely triggering a proresolution feed-forward loop in the periodontium.
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Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins.
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