a borderline significant trendp = 0.074
Meta-analysis suggested a significant reduction in plasma concentrations of total cholesterol (WMD: −9.49 mg/dL, 95% CI: −17.07, −1.92, p = 0.014) and a borderline significant trend in reduction of LDL-C (WMD: −4.67 mg/dL, 95% CI: −9.78, 0.45, p = 0.074) following L-carnitine supplementation ( Fig. 5 ).