Notably, however, the combined cdc-42; gdi-1 RNAi treated worms showed a trend of further reducing invadopodia formation rate ( Table 2 ) and mispolarization of F-actin compared to loss of cdc-42 or gdi-1 alone ( Fig 5A–5D and 5F ).
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A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation.
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