Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

Eur J Hum Genet · 2016 · PMC4717209 · PMID 25920553

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP <0.05actually significant

14 We defined replicated SNPs as those showing nominally significant association ( P <0.05) and a consistent direction of effect.

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highly significantno p-value reported

Results Genetic association As expected, a highly significant association was observed within the HLA region in our study of 425 Irish coeliac patients and 453 population controls.

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