Barely Significant
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Early-stage atherosclerosis in poloxamer 407-induced hyperlipidemic mice: pathological features and changes in the lipid composition of serum lipoprotein fractions and subfractions.

Lipids Health Dis · 2016 · PMC4724105 · PMID 26801626

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Cathepsin B activity in liver and heart tissue The specific activity of cathepsin B in liver tissue increased modestly 24 h after stopping P-407 treatment for 1 month, although it did not reach statistical significance when compared to control (data not shown).

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