Role of Muscarinic Acetylcholine Receptors in Serial Feature-Positive Discrimination Task during Eyeblink Conditioning in Mice.

Post-learning administration of scopolamine did not impair the pre-acquired EMG pattern in cued trials, but led to nominal increase in average EMG amplitude values in non-cued trials, which did not reach statistical significance (cued trials: 518.6 ± 57.54% and 476.8 ± 83.2% for acquisition-7 and expression-1, respectively, non-cued trials: 215 ± 60.08% and 257.48 ± 64.55% for acquisition-7 and expression-1, respectively; P>0.05, paired t-test, Fig 3Aa ).

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