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Increased Dickkopf-1 in Recent-onset Rheumatoid Arthritis is a New Biomarker of Structural Severity. Data from the ESPOIR Cohort.

Sci Rep · 2016 · PMC4726234 · PMID 26785768

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showed a trendno p-value reported
Patients with CRP level >6 mg/L showed a trend for increased DKK-1 level, but mean DKK-1 level was still higher for patients with normal than increased CRP level (28.7 ± 13.9 vs 26.5 ± 11.7 pmol/L; P trend = 0.06) ( Fig. 3 ).

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