Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin.

Here, we demonstrated for the first time that the differentiation potential of MSCs was preserved even after exposure to high doses of cisplatin, and we did not find a general dose-dependent reduction of the differentiation capabilities: While the adipogenic differentiation was found to be reduced at least after treatment with high doses of cisplatin, MSCs showed a trend towards increased osteogenic differentiation after cisplatin treatment.

also in 53,322 other papers