Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice.

Sci Rep · 2016 · PMC4726391 · PMID 26806603

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

close to significancep = 0.054so close (0.05 < p ≤ 0.1)

1l ; n = 8 KO MIR50 0.37 ± 0.010; t-test p < 0.05) and was close to significance with respect to KO VEH (t-test p = 0.054).

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showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

GABA-currents recorded in KO UNT-oocytes showed a trend towards a decrease with respect to WT UNT-injected oocytes ( Fig. 6f , WT UNT, 100 ± 3.51%, n = 90; KO UNT, 87.21 ± 5.93%, n = 77, p = 0.057), while EC 50 and n H ( Fig. 6g ) remained similar (WT UNT, EC 50 = 93.74 ± 5.21 μM, n H = 1.16 ± 0.05, n = 13; KO UNT, EC 50 = 97.8 ± 4.30 μM, n H = 1.24 ± 0.06, n = 18).

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