Figure 3 C reveals a strong trend for specific upregulation of expression of the whole cluster of five genes in the ITD+ samples (shown in red), with a modest upregulation of MED16 , which harbors the specific DHS, and no upregulation of the flanking genes.
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Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature.
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