The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders.

A list of observed DNA variants and their effect on the hepatic copper score is presented in Table 1 . The five nominally significant variations ( P ≤0.05) were genotyped in an independent cohort of 59 Labrador retrievers ( Table 1 ; Table S1 ).

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