Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia.

Dis Model Mech · 2016 · PMC4728336 · PMID 26586530

Europe PMC DOI

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closest p

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The sentences

did not reach statistical significanceno p-value reported

Although there was a tendency for an increase of SREBF2 expression as well as that of its main target genes, HMGCR , PCSK9 and, to a lesser extent, LDLR , in S127R HLCs compared with controls, it did not reach statistical significance.

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