Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility.

PLoS Genet · 2016 · PMC4731077 · PMID 26820313

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hedged sentences

0.0007

closest p · 0.0× alpha

0.0007

boldest claim

The sentences

highly significantP = 0.0007actually significant

Also brain tumors and/or sarcomas were overrepresented in the carrier families (28.6%, Table 2 ); the difference being highly significant when compared to the incidence of these cancers in the analyzed cohorts (5.1%, P = 0.0007, OR 7.4 95% CI 2.7–19.9).

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showed a trendno p-value reported

The MCHP1 mutation carrier breast tumors ( n = 22, S3 Table ) also showed a trend towards triple-negativity (i.e.

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