Inhalation of naphthalene causes olfactory and respiratory epithelial nasal tumors in rats (but not in mice) ( NTP, 1992 , 2000 ); there was a significant increase in neuroblastomas of the olfactory tissue in females and a significant trend with dose in both sexes, and males exhibited a significant increase in adenomas of the nasal respiratory epithelium at all exposure levels.
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Hypothesis-based weight-of-evidence evaluation and risk assessment for naphthalene carcinogenesis.
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