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Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.

Onco Targets Ther · 2016 · PMC4734822 · PMID 26869800

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a strong trendno p-value reported
45 Although the mutational frequency of NRAS is very low, there is a strong trend toward a negative response to anti-EGFR antibodies therapy in populations for wild-type KRAS/mutational NRAS.

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