Barely Significant
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Physicochemical origin of high correlation between thermal stability of a protein and its packing efficiency: a theoretical study for staphylococcal nuclease mutants.

Biophys Physicobiol · 2015 · PMC4736840 · PMID 27493849

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a strong trendno p-value reported
Though | ΔV ex | is dependent on V ex of the unfolded state as well as that of the folded state, there is a strong trend that | ΔV ex | becomes smaller as V ex of the folded state decreases.

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