Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.

J Thromb Haemost · 2015 · PMC4737230 · PMID 25858425

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a clear trendno p-value reported

However, it is noteworthy that, although not significant, a clear trend towards reduction in GSK3α/β phosphorylation was seen at 90 s in the presence of PD0325901, and this may explain why inhibition of ERK activation by PD0325901 also reduces platelet aggregation by CLEC‐2 stimulation.

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