nominally significantP =0.03
Look-ups in consortium data showed a nominally significant association for the leptin-decreasing allele of rs10487505 with higher BMI in the GIANT Consortium ( P =0.03, N =221,677), as well as with increased risk of early-onset obesity ( P =0.04, N =13,848) and higher birth weight ( P =0.02, N =26,836) in the EGG Consortium ( Supplementary Table 7 ).