Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis.

PLoS One · 2016 · PMC4740455 · PMID 26840601

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did not reach statistical significanceno p-value reported

Further histological evaluation of plaque burden based on specific stains revealed that treatment with 17-βE in the CREKA nanoemulsion form significantly decreased plaque lipid content, a difference that did not reach statistical significance with the 17-βE solution and the blank nanoemulsiuon system ( Fig 3 ).

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