Our data raises the idea that BRCA1 Q356R may be significant in the context of other variants that weaken DDR.
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Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer.
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Sun and colleagues developed a list of single nucleotide polymorphisms (SNPs) affecting sex hormone metabolism, some of which showed significant or near-significant linkage to prostate cancer aggressiveness at diagnosis [ 21 ].