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The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells.

PLoS One · 2016 · PMC4743835 · PMID 26849807

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Compared to controls, 1 μM rottlerin increased apoptosis by 1.0-fold at 24 h and 1.4-fold at 48 h; and 2.5 μM rottlerin increased apoptosis by 1.1-fold at 24 h and 1.5-fold at 48 h, but these increases did not reach statistical significance.

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