Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.

Compared with the breast cancer patients with fewer than two relatives affected by breast cancer or unilateral breast cancer, the overall mutation rates were higher in the patients with two or more relatives affected by breast cancer or bilateral breast cancer, but these differences did not reach statistical significance ( P = 0.148 and P = 0.115, respectively).

also in 111,027 other papers