Nociceptor Sensitization Depends on Age and Pain Chronicity(1,2,3).

eNeuro · 2016 · PMC4745182 · PMID 26866058

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a strong trendno p-value reported

In contrast, we found that C fibers from aged animals exhibited a strong trend toward sensitization to mechanical stimuli following acute CFA inflammation compared with PBS controls, but this relationship was not statistically significant ( Fig. 2C l ; p = 0.0505 with two-way ANOVA; n = 25 fibers for PBS and n = 32 fibers for CFA; data obtained from three animals in each group).

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