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Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine.

Oncotarget · 2015 · PMC4747358 · PMID 26510912

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A recent Phase II study of sorafenib and everolimus represents the first positive study for relapsed osteosarcoma in decades, but even this study did not reach statistical significance for the primary outcome [ 3 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.