Our study using hourly temperature data in a large international study population corroborates the findings of a Taiwanese study with known hourly temperature data at ICH onset which showed a trend of increased ICH occurrence towards the lower temperature and is also consistent with prior investigations and clinical observation of a peak ICH occurrence in the winter due in part to the trigger effect of low ambient temperature on the risk of ICH onset at particular times of the day [ 2 – 5 , 25 ].
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Low Ambient Temperature and Intracerebral Hemorrhage: The INTERACT2 Study.
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