Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity.

J Infect Dis · 2016 · PMC4747614 · PMID 26450421

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Ex vivo IFN-γ ELISpot responses to PPD 2 weeks after challenge showed a trend toward an inverse correlation between the number of BCG detected in the skin biopsy specimens by qPCR and the number of CFU, consistent with our previous findings with this model [ 10 ].

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