In China, there is an increasing trend in both morbidity and mortality rates of CRC ( 2 ).
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Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer.
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The sentences
The expression level of JAM-2 decreased as TNM stage (P=0.32) and nodal stage (P=0.19) and levels of JAM-2 transcript were lower in node-positive tumours than in node-negative tumours, lower in tumours with distant metastasis than those without metastasis, and much lower in the patients who had died of colon cancer than in those who remained alive and well, but this did not reach statistical significance.