By moonlighting in the nucleus, villin regulates epithelial plasticity.

Mol Biol Cell · 2016 · PMC4751603 · PMID 26658611

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quite significantno p-value reported

Thus the benefit of understanding the molecular mechanisms that guide the regulation of the EMT is quite significant ( McCaffrey and Macara, 2011 ; Muthuswamy and Xue, 2012 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.