2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing.

After a mean 1.4-year follow-up, the prolonged detection group (Arm C) was associated with a reduction in treated VT/VF leading to a 76% reduction in the primary endpoint of the first inappropriate therapy ( P The Avoid Delivering Therapies for Non-Sustained Arrhythmias in ICD Patients III (ADVANCE III) trial reported that a long detection was associated with a highly significant reduction of overall therapies (appropriate and inappropriate ATP and/ or shocks), inappropriate shocks, and all-cause hospitalizations [97] .

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Patients within the DDDR-70 group (with paced and sensed atrioventricular delays of 170 and 150 ms, respectively, in most of the DDDR group patients) showed a trend toward higher mortality and an increased incidence of HF compared with the patients programmed to ventricular backup pacing—the VVI-40 group.

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