Transcriptome wide analyses reveal a sustained cellular stress response in the gill tissue of Trematomus bernacchii after acclimation to multiple stressors.

As to cell proliferation, fish in the 7d multi-stressor treatment demonstrated a strong trend of down-regulation overall (4 up-regulated, 20 down-regulated) (Fig. 6 , Additional file 5 : Table S5) that suggests cell cycle arrest in response to stress extends beyond the initial time-frame proposed by Sleadd and colleagues [ 39 ] .

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