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Dynamic Drusen Remodelling in Participants of the Nutritional AMD Treatment-2 (NAT-2) Randomized Trial.

PLoS One · 2016 · PMC4762680 · PMID 26901353

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Women tended to show a greater reduction in total drusen diameter in the inner subfield with the CFH polymorphism (TT) genotype than with the heterozygous or homozygous risk alleles (CT\CC) (p = 0.03), Concerning drusen area remodeling, we found that drusen area in the inner subfield was also reduced in older patients (r = -0.17) and in women (p = 0.01), but these associations did not reach statistical significance.

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