Although significant associations between the three FTO genotypes and adiposity measures were found, none of the FTO genotype by PA interaction assessments revealed nominally significant associations.
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Physical activity and FTO genotype by physical activity interactive influences on obesity.
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Discussion In the present study, we demonstrated that the obesity measures BMI, fat mass, hip circumference, and waist circumference are correlated with PA as well as with three FTO variants, and that there was some trend toward significance in the interaction effects between PA and FTO genetic variants on these four obesity-related phenotypes in a Latino population.