First trough level of infliximab at week 2 predicts future outcomes of induction therapy in ulcerative colitis-results from a multicenter prospective randomized controlled trial and its post hoc analysis.

J Gastroenterol · 2016 · PMC4766223 · PMID 26162647

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.2870

boldest claim

The sentences

marginal significancep = 0.054so close (0.05 < p ≤ 0.1)

The clinical remission rate showed marginal significance ( p = 0.054), whereas MH was significantly more frequent with IFX than placebo ( p = 0.006).

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did not reach statistical significancep = 0.287not close (p > 0.1)

Response rate at week 8 in acute severe cases ( n = 18, Mayo score ≥11) was similar to that in the entire study population, although it did not reach statistical significance because of the limited number of patients [54.5 % (6/11) in the IFX group versus 28.6 % (2/7) in the placebo group, p = 0.287].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.