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Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.

Bone Res · 2016 · PMC4772748 · PMID 26962465

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Col2-cre;Lrp6 Fl/FL female mice also weighed significantly less than controls (17% reduction), whereas male mice displayed a downward trend (4% decrease) that did not reach statistical significance.

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