highly significantP = 10 −92
Approximately 1,000 of the inducible genes had an iDHS within 150 kb of the TSS, and nearly 500 of these elements were located within just 25 kb which was highly significant ( P = 10 −92 ) (Fig 4 E), further signifying a role for the iDHSs as inducible enhancers of these genes.