EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.

The magnitude of increase in α-angle was not significantly different between EspP S263A - and EspP WT -treated whole blood at 0.5 and 2 h (P = 0.104 and 0.144, respectively) and was only marginally significant at 4 h (P = 0.046).

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