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Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content.

Pharmacogenomics J · 2016 · PMC4775436 · PMID 26323597

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The mean activity for the CYP2C19*1B/*2A diplotype was 35.4% lower than that of the CYP2C19*1B/*1B diplotype, although the difference did not reach statistical significance.

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