A low-carbohydrate high-fat diet increases weight gain and does not improve glucose tolerance, insulin secretion or β-cell mass in NZO mice.

Nutr Diabetes · 2016 · PMC4775822 · PMID 26878317

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a clear trendno p-value reported

There was also a clear trend for higher fasting plasma insulin levels in LCHFD-fed mice ( Figure 3c ).

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