Soluble amyloid beta oligomers block the learning-induced increase in hippocampal sharp wave-ripple rate and impair spatial memory formation.

Sci Rep · 2016 · PMC4779992 · PMID 26947247

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0680

boldest claim

The sentences

close to significancep = 0.058so close (0.05 < p ≤ 0.1)

Finally, comparison of occurrence of SWRs during all time bins between control and Aβo-injected animals revealed significant difference for the post-encoding period (t 12 = 2.48, p = 0.029) and a difference close to significance for the post-test period (t 12 = 2.09, p = 0.058) with all other measurements remaining similar between the two groups (p > 0.2).

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approaching significancep = 0.068so close (0.05 < p ≤ 0.1)

Also direct comparisons of the SWRs occurrence rates in all SWS bins between the two groups showed significant difference for the post-encoding period (t 12 = 2.41, p = 0.032), a difference approaching significance for the post-test period (t 12 = 2.0, p = 0.068) and no difference for all remaining bins (p > 0.2).

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