Lesion Size Is Exacerbated in Hypoxic Rats Whereas Hypoxia-Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor Increase in Injured Normoxic Rats: A Prospective Cohort Study of Secondary Hypoxia in Focal Traumatic Brain Injury.

Front Neurol · 2016 · PMC4780037 · PMID 27014178

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showed a trendp = 0.10so close (0.05 < p ≤ 0.1)

In our study the lesion area devoid of nuclear DAPI signal was not statistically different in hypoxic or normoxic animals, but only showed a trend toward larger lesion after hypoxia ( p = 0.10).

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