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The Protective Effect of Icariin on Mitochondrial Transport and Distribution in Primary Hippocampal Neurons from 3× Tg-AD Mice.

Int J Mol Sci · 2016 · PMC4783897 · PMID 26828481

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With icariin treatment, the percentage of total motile mitochondria in Tg cells increased to 31.6% ± 5.2% ( p < 0.05 as compared with Tg control group), although the increases in anterogradely moving mitochondria (16.6% ± 6.0%, p = 0.227 as compared with Tg control group) and retrogradely moving mitochondria (15.0% ± 4.3%, p = 0.145 as compared with Tg control group) did not reach statistical significance ( Supplementary Movie 3 ).

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