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Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications.

J Pathol · 2016 · PMC4784173 · PMID 26648175

1
hedged sentence
0.1100
closest p · 2.2× alpha
0.1100
boldest claim

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did not reach statistical significancep = 0.11not close (p > 0.1)
However, following siATF6β treatment, we observed a 65% increase of PlGF mRNA in untreated cells, although the increase did not reach statistical significance ( p = 0.11) in the thapsigargin‐treated condition (Figure 5 B).

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