However, following siATF6β treatment, we observed a 65% increase of PlGF mRNA in untreated cells, although the increase did not reach statistical significance ( p = 0.11) in the thapsigargin‐treated condition (Figure 5 B).
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Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications.
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