highly significantp-values ≤ 10 −53
As expected, all 6 biosets exhibited highly significant similarity to the STAT5b biomarker (p-values ≤ 10 −53 ).
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Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event.
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0.0000
0.3300
The sentences
approached significancep-value = 4E-4
The masculinization approached significance (p-value = 4E-4) in 5 wk old Trim24-null mice vs. wild-type mice from the same study ( GSE19675 ).
marginally significantp-value = 0.33
Biosets characterizing GH receptor truncated at amino acid 569 ( GSE11396 , GSE988 ), were either not significant or were marginally significant for feminization (p-value = 0.33 and 3.8E-05, respectively), consistent with the weak to moderate effects of this mutant on GH-dependent phosphorylation of STAT5b [ 54 ].